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IN VITRO CELL BASED RESEARCH


IN VITRO CELL BASED RESEARCH

Bisvani with its state of the art Cell biology, Molecular biology and Microbiology facilities is offering exclusive range of cruelty free in vitro research services as an alternative to animal models to fasten the drug discovery process in a cost effective manner.

At Bisvani, our cell repository is equipped with more than 60 cell lines and 50 microbial cultures to give an better choice to our clients in designing their research activities in customized manner. Our technical expertise and understanding about the regulatory guidelines made us the favourite destination especially for the clients from Ayurvedic, Herbal and Cosmetic business.

At Bisvani, with an special focus towards cosmetics and personal care products we upgrade ourselves to the recent advancements like reconstructed human skin models (EpiSkin, SkinEthic and EpiDerm) to evaluate the safety and efficacy.


EFFICACY STUDIES

  • Anti microbial
  • Anti viral
  • Cytotoxicity
  • Cell proliferation
  • Cancer
  • Diabetes
  • Hepatoprotection
  • Obesity
  • Immunomodulatory
  • Inflammation
  • Drug permeability (CaCo-2 cell model)
  • Gene expression analysis
  • Enzyme and Immunoassays (ELISA)
  • Skin Lightening
  • Sun Protection Factor (SPF)
  • Anti-aging
  • Skin tightening
  • Psoriasis
  • Scar/wound healing
  • Anti-acne
  • Anti-Dandruff
  • Deodorant
  • Skin Moisturizing
  • Skin pigmentation
  • Hair growth/anti-hair fall
  • Dermal permeation/absorption using EpiskinTM / EpidermTM/Porcine skin

TOXICITY/SAFETY STUDIES

  • 3T3 NRU phototoxicity (Skin irritation)
  • Skin Irritation studies in human reconstructed skin models (EpiSkin, SkinEthic etc)

Genotoxicity

  • AMES test (BRMT)
  • Chromosomal aberration in CHO-K1 cells